Search on: NODAL SIGNALING LIGANDS 
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Descriptor English:   Nodal Signaling Ligands 
Descriptor Spanish:   Ligandos de Señalización Nodal 
Descriptor Portuguese:   Ligantes da Sinalização Nodal 
Synonyms English:   Nodal Signaling Proteins
Signaling Proteins, Nodal  
Tree Number:   D12.644.276.954.550
D12.776.467.942.550
D23.529.942.550
Definition English:   Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE. 
History Note English:   2009 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53145 
Unique Identifier:   D055456 

Occurrence in VHL:
 

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